SCHEMBL4253619

SCHEMBL4253619

CCCOC(=O)/C=C(\Oc1ccc([N+](=O)[O-])cc1)C(=O)OCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.53
CTNNB1 P35222 1/20 0.53
MGLL Q99685 2/20 0.48
GAA P10253 1/20 0.46
KMT2A Q03164 3/20 0.43
LMNA P02545 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 6/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
MAPK1 P28482 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
HTR2A P28223 1/20 0.42
PKM P14618 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HGFAC Q04756 1/20 0.41
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4252403 1.00 BCL9 (0.53) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4252406 1.00 BCL9 (0.53) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4252354 0.94 MGLL (0.53) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4256738 0.94 MGLL (0.53) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4252357 0.94 MGLL (0.53) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4249035 0.90 MGLL (0.54) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4251619 0.90 MGLL (0.54) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4249031 0.90 MGLL (0.54) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4250585 0.87 BCL9 (0.52) BCL9CTNNB1MGLLGAAKMT2A
SCHEMBL4252686 0.87 BCL9 (0.52) BCL9CTNNB1MGLLGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL BCL9 4330/4885CTNNB1 1544/4885MGLL 4156/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL BCL9 4330/4885CTNNB1 1544/4885MGLL 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.