Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4253889 | 0.86 | HSD17B10 (0.58) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL6954317 | 0.85 | HSD17B10 (0.60) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL10718048 | 0.85 | HSD17B10 (0.60) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL6954649 | 0.85 | HSD17B10 (0.60) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL4256521 | 0.85 | HSD17B10 (0.60) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL10576688 | 0.83 | HSD17B10 (0.55) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL2692039 | 0.82 | PPARG (0.53) | TSHRHSD17B10HSD11B1ACHEPPARG | |
| SCHEMBL1640243 | 0.80 | LIPG (0.41) | PPARGALDH1A1HPGD | |
| SCHEMBL29939361 | 0.80 | HSD11B1 (0.63) | TSHRHSD17B10HSD11B1ACHEALDH1A1 | |
| SCHEMBL565466 | 0.80 | ESR2 (0.50) | TSHRALDH1A1HPGDSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155496-A1 | FILAMENT OR FIBRE | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2009-06-18 | — | — | US | disclosed |
| US-20070128437-A1 | FILAMENT OR FIBRE | KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) | 2007-06-07 | — | — | US | disclosed |
| EP-1753899-A1 | A FILAMENT OR FIBRE | Koninklijke Philips Electronics N.V. (NL) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005113866-A1 | A FILAMENT OR FIBRE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2005-12-01 | — | — | WO | disclosed |