Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770996 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6242053 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL6237613 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10935342 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL1104430 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10934245 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10937702 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10934552 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10933452 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 | |
| SCHEMBL10937597 | 0.89 | PLA2G1B (0.53) | PSMD14PLA2G1BMMP2ATG4BHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984121-B1 | NON-LEACHING SURFACE-ACTIVE FILM COMPOSITIONS FOR MICROBIAL ADHESION PREVENTION | HYDROMER INC (US) | 2019-05-08 | — | — | EP | claimed |
| JP-2009523890-A | — | — | 2009-06-25 | — | — | JP | claimed |
| EP-1984121-A2 | NON-LEACHING SURFACE-ACTIVE FILM COMPOSITIONS FOR MICROBIAL ADHESION PREVENTION | Hydromer, Inc. (US) | 2008-10-29 | — | — | EP | claimed |
| WO-2007084452-A2 | NON-LEACHING SURFACE-ACTIVE FILM COMPOSITIONS FOR MICROBIAL ADHESION PREVENTION | HYDROMER, INC. (US) | 2007-07-26 | — | — | WO | claimed |
| US-20070166344-A1 | Non-leaching surface-active film compositions for microbial adhesion prevention | HYDROMER, INC. | 2007-07-19 | — | — | US | claimed |
| EP-1984121-B1 | NON-LEACHING SURFACE-ACTIVE FILM COMPOSITIONS FOR MICROBIAL ADHESION PREVENTION | HYDROMER INC (US) | 2019-05-08 | — | — | EP | disclosed |
| EP-1984121-A2 | NON-LEACHING SURFACE-ACTIVE FILM COMPOSITIONS FOR MICROBIAL ADHESION PREVENTION | Hydromer, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084452-A2 | NON-LEACHING SURFACE-ACTIVE FILM COMPOSITIONS FOR MICROBIAL ADHESION PREVENTION | HYDROMER, INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070166344-A1 | Non-leaching surface-active film compositions for microbial adhesion prevention | HYDROMER, INC. | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166344-A1 | Non-leaching surface-active film compositions for microbial adhesion prevention | ICAM1, CD44, NONO | PSMD14 1570/4885PLA2G1B 3873/4885MMP2 366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.