SCHEMBL4254646

SCHEMBL4254646

CCC(C)OC(=O)C(I)C(I)C(=O)OC(C)CC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
FAAH O00519 1/20 0.34
TSHR P16473 2/20 0.31
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
CHRM1 P11229 2/20 0.31
TBXA2R P21731 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30
LMNA P02545 1/20 0.30
CYP2C9 P11712 1/20 0.30
GALR3 O60755 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779893 0.80 MAPT (0.43) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL2980611 0.80 MAPT (0.43) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL1216964 0.80 MAPT (0.43) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL6741818 0.79 MAPT (0.40) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL4439936 0.78 MAPT (0.42) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL7223633 0.78 MAPT (0.42) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL702238 0.78 MAPT (0.42) MAPTFAAHTSHRCHRM2CHRM4
Magnesium SCHEMBL29456102 0.78 MAPT (0.42) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL2978632 0.78 MAPT (0.42) MAPTFAAHTSHRCHRM2CHRM4
SCHEMBL28889016 0.78 MAPT (0.42) MAPTFAAHTSHRCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL MAPT 4765/4885FAAH 2814/4885TSHR 1710/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL MAPT 4765/4885FAAH 2814/4885TSHR 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.