SCHEMBL425487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16519527	0.84	LMNA (0.65)	KMT2ACA12CA1CA2CA3
	SCHEMBL10153819	0.84	TSHR (0.61)	KMT2ACA12CA1CA2CA3
	SCHEMBL1804387	0.82	CA1 (0.50)	KMT2ATDP1CA12CA1CA2
	SCHEMBL29167246	0.82	CA12 (0.60)	KMT2ACA12CA1CA2CA3
	SCHEMBL20779633	0.82	CA1 (0.50)	KMT2ATDP1CA12CA1CA2
	SCHEMBL3017872	0.82	LMNA (0.49)	KMT2ATDP1CA12CA1CA2
	SCHEMBL31347291	0.82	CA1 (0.61)	KMT2ATDP1CA12CA1CA2
	SCHEMBL22612213	0.82	CA1 (0.61)	KMT2ATDP1CA12CA1CA2
	SCHEMBL14378094	0.80	KMT2A (0.54)	KMT2ATDP1LMNASMN1; SMN2HTT
	SCHEMBL22747086	0.80	CA12 (0.47)	KMT2ATDP1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.