Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29523356 | 0.82 | GSK3B (0.44) | KDM4EGAAMAPTMAPK1 | |
| SCHEMBL16070373 | 0.80 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AATM | |
| Methyl Alcohol SCHEMBL28478479 | 0.76 | NPC1 (0.89) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL8519975 | 0.76 | NPC1 (0.48) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9000455 | 0.76 | MAPT (0.39) | NPC1RAB9AATMKDM4EGAA | |
| SCHEMBL229328 | 0.76 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9000452 | 0.76 | MAPT (0.39) | NPC1RAB9AATMKDM4EGAA | |
| SCHEMBL31560044 | 0.76 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9394256 | 0.76 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL229329 | 0.76 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814854-A4 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1814854-A1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC Foundation For Research Development (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006050264-A1 | CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2006-05-11 | — | — | WO | disclosed |
| US-5834230-A | Viscosity Probe | MCGILL UNIVERSITY (CA) | 1998-11-10 | — | — | US | disclosed |