Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.34 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717165 | 0.85 | PTPN1 (0.37) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL8520461 | 0.78 | RAB9A (0.55) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL4940752 | 0.78 | NFE2L2 (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL4940765 | 0.78 | NFE2L2 (0.43) | MEN1KMT2AKDM4E | |
| SCHEMBL10583374 | 0.76 | CDK4 (0.44) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11128934 | 0.76 | PTPN1 (0.34) | MEN1KMT2AKDM4E | |
| SCHEMBL4255050 | 0.76 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL473072 | 0.75 | ALDH1A1 (0.40) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL3257572 | 0.73 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9811806 | 0.72 | NFKB1 (0.47) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11171908-A | — | — | None | — | — | JP | disclosed |
| JP-11171909-A | — | — | None | — | — | JP | disclosed |
| JP-H11171909-A | PHOTOPOLYMERIZABLE COMPOSITION AND SHEET FOR RECORDING | BROTHER IND LTD | 1999-06-29 | — | — | JP | disclosed |
| JP-H11171908-A | PHOTOPOLYMERIZABLE COMPOSITION AND SHEET FOR RECORDING | BROTHER IND LTD | 1999-06-29 | — | — | JP | disclosed |
| US-5840859-A | (Aminostyryl)pyridinium compounds for radiolabelling cell membranes | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1997002246-A1 | (AMINOSTYRYL)PYRIDINIUM COMPOUNDS FOR RADIOLABELLING CELL MEMBRANES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-01-23 | — | — | WO | disclosed |