Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288003 | 0.90 | PTGS2 (0.63) | LMNAHPGDESR1ESR2PTGS2 | |
| SCHEMBL892055 | 0.90 | PTGS2 (0.63) | LMNAHPGDESR1ESR2PTGS2 | |
| SCHEMBL1345582 | 0.90 | PTGS2 (0.63) | LMNAHPGDESR1ESR2PTGS2 | |
| Hydrochloric Acid SCHEMBL28716582 | 0.88 | PTGS2 (0.61) | LMNAHPGDESR1ESR2PTGS2 | |
| SCHEMBL9232479 | 0.88 | PTGS2 (0.61) | LMNAHPGDESR1ESR2PTGS2 | |
| SCHEMBL9232475 | 0.88 | PTGS2 (0.61) | LMNAHPGDESR1ESR2PTGS2 | |
| SCHEMBL9234136 | 0.88 | PTGS2 (0.61) | LMNAHPGDESR1ESR2PTGS2 | |
| SCHEMBL7704968 | 0.86 | PTGS2 (0.71) | LMNAMAPTHPGDESR1PTGS2 | |
| SCHEMBL5313395 | 0.86 | PTGS2 (0.71) | LMNAMAPTHPGDESR1PTGS2 | |
| SCHEMBL1678786 | 0.84 | PTGS2 (0.74) | LMNAESR1PTGS2PTGS1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569601-B2 | Cycloalkylidene compounds as modulators of estrogen receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-04 | — | — | US | disclosed |
| US-20070213348-A1 | Chemical Compounds | BRITTON JONATHAN E | 2007-09-13 | — | — | US | disclosed |
| EP-0923527-A1 | A PROCESS FOR THE PREPARATION OF 2-(3-BENZOYL-PHENYL)-PROPIONIC ACID STARTING FROM ARYL-OLEFINS | Dompé S.P.A. (IT) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998005623-A1 | A PROCESS FOR THE PREPARATION OF 2-ARYL-PROPIONIC AND 2-ARYL-ACETIC ACIDS STARTING FROM ARYL-OLEFINS | DOMPE' S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213348-A1 | Chemical Compounds | GPER1, ESR2, ESR1 | LMNA 4504/4885MAPT 3451/4885HPGD 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.