Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251108 | 1.00 | TAS1R3 (0.59) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL4250725 | 0.90 | TAS1R3 (0.55) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL4251095 | 0.90 | TAS1R3 (0.55) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL445758 | 0.90 | TAS1R3 (0.61) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL444856 | 0.90 | TAS1R3 (0.61) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL4251079 | 0.89 | PPARG (0.46) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL4255571 | 0.87 | PPARG (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4254174 | 0.87 | PPARG (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4257552 | 0.85 | TAS1R3 (0.46) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR | |
| SCHEMBL4257472 | 0.85 | TAS1R3 (0.46) | TAS1R3TAS1R1SMN1; SMN2KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023798-A1 | THIOHYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023798-A1 | THIOHYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC8, HDAC3 | TAS1R3 3722/4885TAS1R1 3753/4885SMN1; SMN2 3469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.