SCHEMBL4255258

SCHEMBL4255258

COC(=O)CCc1ccc(OCc2ccc(F)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.60
FFAR1 O14842 5/20 0.58
EPHX2 P34913 1/20 0.58
NR4A2 P43354 1/20 0.57
PARP10 Q53GL7 1/20 0.56
FFAR4 Q5NUL3 3/20 0.54
ADRB2 P07550 1/20 0.52
ADRB1 P08588 1/20 0.52
APP P05067 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2723440 0.87 CYP11B1 (0.57) MAOBFFAR1ADRB2ADRB1
SCHEMBL15679198 0.87 FFAR1 (0.60) MAOBFFAR1PARP10FFAR4ADRB2
SCHEMBL1745247 0.87 FFAR1 (0.72) MAOBFFAR1EPHX2FFAR4
SCHEMBL1747136 0.87 FFAR1 (0.72) MAOBFFAR1EPHX2FFAR4
SCHEMBL1745397 0.85 FFAR1 (0.58) FFAR1FFAR4ADRB2ADRB1
SCHEMBL1745363 0.85 FFAR1 (0.58) FFAR1FFAR4ADRB2ADRB1
SCHEMBL2828491 0.85 FFAR1 (0.71) MAOBFFAR1FFAR4ADRB2ADRB1
SCHEMBL1745141 0.85 FFAR1 (0.58) MAOBFFAR1PARP10FFAR4ADRB2
SCHEMBL5090748 0.85 MAOB (0.63) MAOBFFAR1NR4A2PARP10APP
SCHEMBL9627732 0.85 MAOB (0.68) MAOBFFAR1EPHX2NR4A2PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009055932-A1 SUBSTITUTED PHENYLPROPIONIC ACIDS AS STIMULATORS OF HEMATOPOIESIS AND ERYTHROPOIESIS PROMETIC BIOSCIENCES INC. (CA) 2009-05-07 WO disclosed