Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255302 | 1.00 | ADRB2 (0.77) | ADRB2 | |
| SCHEMBL4253223 | 0.95 | ADRB2 (0.84) | ADRB2 | |
| SCHEMBL4253219 | 0.95 | ADRB2 (0.84) | ADRB2 | |
| SCHEMBL4253675 | 0.92 | ADRB2 (0.65) | ADRB2 | |
| SCHEMBL4255237 | 0.92 | ADRB2 (0.65) | ADRB2 | |
| SCHEMBL4260245 | 0.87 | ADRB2 (1.00) | ADRB2 | |
| SCHEMBL4255024 | 0.87 | ADRB2 (0.81) | ADRB2 | |
| SCHEMBL4255044 | 0.87 | ADRB2 (0.71) | ADRB2 | |
| SCHEMBL4255017 | 0.87 | ADRB2 (0.81) | ADRB2 | |
| SCHEMBL4260248 | 0.87 | ADRB2 (1.00) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624868-B9 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2009-08-12 | — | — | EP | claimed |
| EP-1624868-B1 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2008-11-12 | — | — | EP | claimed |
| EP-1477167-A1 | [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists | Pfizer Limited (GB) | 2004-11-17 | — | — | EP | disclosed |