⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35180 | 0.72 | — | — | |
| SCHEMBL2997846 | 0.72 | — | — | |
| SCHEMBL3463060 | 0.69 | — | — | |
| SCHEMBL2029533 | 0.69 | — | — | |
| SCHEMBL6962197 | 0.69 | — | — | |
| SCHEMBL421337 | 0.67 | HDAC3 (0.38) | — | |
| SCHEMBL6838010 | 0.67 | — | — | |
| SCHEMBL4553198 | 0.67 | — | — | |
| SCHEMBL35181 | 0.67 | — | — | |
| SCHEMBL162412 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136162-A1 | INTERMEDIATE AND PROCESSES INVOLVED IN THE PREPARATION OF 2 ' -CYANO-2 ' -DE0XY-N4-PALMIT0YL-1-BETA-ARABIN0FURAN0SYLCYTOSINE | CYCLACEL LIMITED (GB) | 2009-11-12 | — | — | WO | claimed |
| WO-2009136162-A1 | INTERMEDIATE AND PROCESSES INVOLVED IN THE PREPARATION OF 2 ' -CYANO-2 ' -DE0XY-N4-PALMIT0YL-1-BETA-ARABIN0FURAN0SYLCYTOSINE | CYCLACEL LIMITED (GB) | 2009-11-12 | — | — | WO | disclosed |
| EP-1446403-B1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-04-12 | — | — | EP | disclosed |
| US-20050043374-A1 | Aryl substituted oxazolidinones with antibacterial activity | ASTRAZENECA AB (SE) | 2005-02-24 | — | — | US | disclosed |
| EP-1446403-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2004-08-18 | — | — | EP | disclosed |
| US-6624179-B1 | Analyzed by reversed phase liquid chromatography in which a packing comprising silica having chemically bonded thereto an alkyl group selected from trimethyl, octyl and octadecyl, is used as the stationary phase, and a polar solvent selected | ISHIHARA SANGYO KAISHA LTD. (JP) | 2003-09-23 | — | — | US | disclosed |
| EP-0947504-B1 | 16-ENE-VITAMIN D DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0996614-B1 | ACRYLONITRILE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA (JP) | 2003-06-11 | — | — | EP | disclosed |
| WO-2003035648-A1 | ARYL SUBSTITUTED OXAZOLIDINONES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2003-05-01 | — | — | WO | disclosed |
| US-6555699-B2 | Antitumor and antirheumatic agents, high binding affinity | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-0154132-B1 | 6-ALKYLIDENE PENEMS, THEIR PREPARATION AND USE, AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1992-01-08 | — | — | EP | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |
| US-4798828-A | LACTAMASE INHIBITORS | BEECHAM GROUP P.L.C. (GB) | 1989-01-17 | — | — | US | disclosed |
| EP-0078026-B1 | ANTIBIOTIC SYNTHESIS | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0154132-A1 | 6-Alkylidene penems, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-09-11 | — | — | EP | disclosed |
| EP-0150781-A1 | 6-Alkylidene pemens, their preparation and use, and intermediates | BEECHAM GROUP PLC (GB) | 1985-08-07 | — | — | EP | disclosed |
| EP-0120613-A1 | Penem derivatives and precursors | BEECHAM GROUP PLC (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0078026-A2 | Antibiotic synthesis | MERCK & CO. INC. (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4201778-A | 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates | SCHERING CORPORATION (US) | 1980-05-06 | — | — | US | disclosed |
| EP-0001864-A1 | Novel 6-oxygenated-3,20-dioxo-pregnane derivatives, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-05-16 | — | — | EP | disclosed |