SCHEMBL421337

SCHEMBL421337

CCSC(=S)SSC(=S)SCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 13/20 0.38
HDAC4 P56524 13/20 0.38
HDAC1 Q13547 13/20 0.38
HDAC7 Q8WUI4 13/20 0.38
HDAC2 Q92769 13/20 0.38
HDAC10 Q969S8 13/20 0.38
HDAC11 Q96DB2 13/20 0.38
HDAC8 Q9BY41 13/20 0.38
HDAC6 Q9UBN7 13/20 0.38
HDAC9 Q9UKV0 13/20 0.38
HDAC5 Q9UQL6 13/20 0.38
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 2/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2D6 P10635 1/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
PHGDH O43175 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35180 0.86
SCHEMBL11291272 0.78
SCHEMBL28307194 0.78
SCHEMBL31622922 0.75 TDP1 (0.42) ALDH1A1CYP1A2TSHRCYP2C19NOS3
SCHEMBL3463056 0.73
SCHEMBL14102731 0.71
SCHEMBL22657366 0.71 NOS3 (0.46) ALDH1A1CYP1A2TSHRCYP2C19NOS3
SCHEMBL18562073 0.71 CYP1A2 (0.36) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL47735 0.71 HDAC3 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL11760685 0.69 NOS3 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025050013-A1 COVALENT POLYMER-NUCLEIC ACID CONJUGATES FOR MODULATION OF THE RIG-I PATHWAY VANDERBILT UNIVERSITY (US) 2025-03-06 WO disclosed
US-11707483-B2 Micellic assemblies UNIVERSITY OF WASHINGTON (US) 2023-07-25 US disclosed
US-20200147121-A1 MICELLIC ASSEMBLIES UNIVERSITY OF WASHINGTON (US) 2020-05-14 US disclosed
US-10420790-B2 Micellic assemblies UNIVERSITY OF WASHINGTON (US) 2019-09-24 US disclosed
US-10066043-B2 ω-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization UNIVERSITY OF WASHINGTON (US) 2018-09-04 US disclosed
US-20180171056-A1 DIBLOCK COPOLYMERS AND POLYNUCLEOTIDE COMPLEXES THEREOF FOR DELIVERY INTO CELLS ROIVANT SCIENCES LTD. (GB) 2018-06-21 US disclosed
US-9862792-B2 Diblock copolymers and polynucleotide complexes thereof for delivery into cells UNIVERSITY OF WASHINGTON (US) 2018-01-09 US disclosed
US-20170239360-A1 MICELLIC ASSEMBLIES UNIVERSITY OF WASHINGTON (US) 2017-08-24 US disclosed
US-9662403-B2 Micellic assemblies UNIVERSITY OF WASHINGTON (US) 2017-05-30 US disclosed
US-20170145141-A1 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION UNIVERSITY OF WASHINGTON (US) 2017-05-25 US disclosed
US-7695892-B2 Resist composition and pattern-forming method using same FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
US-7695892-B2 Resist composition and pattern-forming method using same FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
WO-2010021770-A1 HETEROGENEOUS POLYMERIC MICELLES FOR INTRACELLULAR DELIVERY UNIVERSITY OF WASHINGTON (US) 2010-02-25 WO disclosed
WO-2009140427-A2 DIBLOCK COPOLYMERS AND POLYNUCLEOTIDE COMPLEXES THEREOF FOR DELIVERY INTO CELLS UNIVERSITY OF WASHINGTON (US) 2009-11-19 WO disclosed
WO-2009140429-A2 MICELLIC ASSEMBLIES UNIVERSITY OF WASHINGTON (US) 2009-11-19 WO disclosed
WO-2009140432-A2 MICELLES FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS UNIVERSITY OF WASHINGTON (US) 2009-11-19 WO disclosed
WO-2009140423-A2 TARGETED POLYMER BIOCONJUGATES UNIVERSITY OF WASHINGTON (US) 2009-11-19 WO disclosed
WO-2009140421-A2 POLYMERIC CARRIER UNIVERSITY OF WASHINGTON (US) 2009-11-19 WO disclosed
US-20080241737-A1 RESIST COMPOSITION AND PATTERN-FORMING METHOD USING SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080241737-A1 RESIST COMPOSITION AND PATTERN-FORMING METHOD USING SAME FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707483-B2 Micellic assemblies UACA, CLPTM1L, BPHL HDAC3 4253/4885HDAC4 4874/4885HDAC1 4546/4885
US-10420790-B2 Micellic assemblies UACA, CLPTM1L, BPHL HDAC3 4253/4885HDAC4 4874/4885HDAC1 4546/4885
US-20200147121-A1 MICELLIC ASSEMBLIES CLPX, VCL, ANXA5 HDAC3 4196/4885HDAC4 4783/4885HDAC1 4629/4885
US-20170239360-A1 MICELLIC ASSEMBLIES UACA, CLPTM1L, BPHL HDAC3 4253/4885HDAC4 4874/4885HDAC1 4546/4885
US-10066043-B2 ω-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization FASN, ALOX5, FGB HDAC3 4064/4885HDAC4 4194/4885HDAC1 4805/4885
US-20180171056-A1 DIBLOCK COPOLYMERS AND POLYNUCLEOTIDE COMPLEXES THEREOF FOR DELIVERY INTO CELLS CHMP4B, PHOSPHO1, EXOSC10 HDAC3 4503/4885HDAC4 4404/4885HDAC1 4776/4885
US-20170145141-A1 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION FASN, ALOX5, ELOVL3 HDAC3 4239/4885HDAC4 4323/4885HDAC1 4847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.