Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255678 | 1.00 | MAPT (0.45) | MAPTALDH1A1L3MBTL1NPSR1HTT | |
| SCHEMBL1403840 | 0.83 | PYGL (0.33) | ALDH1A1HTT | |
| SCHEMBL1403838 | 0.83 | PYGL (0.33) | ALDH1A1HTT | |
| SCHEMBL3365638 | 0.83 | PYGL (0.33) | ALDH1A1HTT | |
| SCHEMBL12156594 | 0.82 | MAPT (0.50) | MAPTALDH1A1L3MBTL1NPSR1CYP4F2 | |
| SCHEMBL17208367 | 0.74 | MAPT (0.41) | MAPTALDH1A1L3MBTL1NPSR1CYP4F2 | |
| SCHEMBL12870395 | 0.72 | MAPT (0.46) | MAPTALDH1A1L3MBTL1NPSR1CYP4F2 | |
| SCHEMBL27831272 | 0.71 | MAPT (0.57) | MAPTALDH1A1L3MBTL1NPSR1HTT | |
| SCHEMBL12870428 | 0.71 | MAPT (0.49) | MAPTALDH1A1L3MBTL1NPSR1CYP4F2 | |
| SCHEMBL1838961 | 0.70 | GRM7 (0.43) | MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135526-A1 | ALPHA-MERCAPTO-AMIDES | NOVARTIS AG (CH) | 2009-11-12 | — | — | WO | disclosed |