Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786263 | 0.88 | MEN1 (0.48) | MEN1MAPTKMT2AGPR84PTPN22 | |
| SCHEMBL14193455 | 0.86 | MEN1 (0.52) | MEN1MAPTKMT2APTPN22NSD2 | |
| SCHEMBL29026237 | 0.84 | MEN1 (0.52) | MEN1MAPTKMT2AGPR84PTPN22 | |
| SCHEMBL14327794 | 0.83 | MCL1 (0.54) | MEN1MAPTKMT2AGPR84PTPN22 | |
| SCHEMBL12786270 | 0.81 | NQO1 (0.46) | MEN1MAPTKMT2AGPR84PTPN22 | |
| SCHEMBL1150949 | 0.81 | MAPT (0.59) | MEN1MAPTKMT2APTPN22NSD2 | |
| SCHEMBL29360295 | 0.81 | NSD2 (0.54) | MEN1MAPTKMT2APTPN22NSD2 | |
| SCHEMBL214870 | 0.81 | NSD2 (0.54) | MEN1MAPTKMT2APTPN22NSD2 | |
| SCHEMBL10028244 | 0.81 | MCL1 (0.57) | MEN1MAPTKMT2ANSD2OPRM1 | |
| SCHEMBL14193453 | 0.81 | MAPT (0.44) | MEN1MAPTKMT2AGPR84PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046915-A1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008011964-A1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |