Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 11/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587524 | 0.90 | MCL1 (0.60) | MCL1ACMSDHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL18704004 | 0.90 | MCL1 (0.60) | MCL1ACMSDHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL14417220 | 0.85 | HSD17B1 (0.61) | MCL1ACMSDHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL57494 | 0.84 | ALDH1A1 (0.54) | MCL1ACMSDCYP1A2TLR8HDAC8 | |
| SCHEMBL28336706 | 0.83 | HPRT1 (0.56) | MCL1ACMSDCYP1A2TLR8HDAC8 | |
| SCHEMBL31707297 | 0.83 | ESR1 (0.68) | HSD17B1HSD17B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7990719 | 0.82 | MCL1 (0.51) | MCL1ACMSDHSD17B1HSD17B2TLR8 | |
| SCHEMBL28114491 | 0.81 | MCL1 (0.46) | MCL1ACMSDHSD17B1HSD17B2CYP1A2 | |
| SCHEMBL28350260 | 0.81 | APP (0.67) | MCL1ACMSDCYP1A2TLR8ALOX5 | |
| SCHEMBL29744510 | 0.81 | APP (0.67) | MCL1ACMSDCYP1A2TLR8ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046915-B1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
| WO-2008011964-A1 | NEW MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SOD1, SLC40A1 | MCL1 4030/4885ACMSD 1730/4885HSD17B1 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.