SCHEMBL4256029

SCHEMBL4256029

CCOC(=O)/C=C(\Oc1cccc([N+](=O)[O-])c1)C(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.53
KMT2A Q03164 4/20 0.52
MEN1 O00255 2/20 0.52
HPGD P15428 2/20 0.52
NPC1 O15118 1/20 0.52
HSP90AA1 P07900 1/20 0.52
PKM P14618 1/20 0.52
CCR6 P51684 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
APOBEC3G Q9HC16 1/20 0.52
ALDH1A1 P00352 4/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 1/20 0.51
GAA P10253 1/20 0.47
F2 P00734 1/20 0.46
HTT P42858 1/20 0.46
HGFAC Q04756 1/20 0.45
CACNA1F O60840 2/20 0.44
CACNA1D Q01668 2/20 0.44
CACNA1S Q13698 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4253509 1.00 GLO1 (0.53) GLO1KMT2AMEN1HPGDNPC1
SCHEMBL4253504 1.00 GLO1 (0.53) GLO1KMT2AMEN1HPGDNPC1
SCHEMBL4250377 0.88 CYP3A4 (0.47) GLO1KMT2AMEN1HPGDNPC1
SCHEMBL4256038 0.88 CYP3A4 (0.47) GLO1KMT2AMEN1HPGDNPC1
SCHEMBL4250385 0.88 CYP3A4 (0.47) GLO1KMT2AMEN1HPGDNPC1
SCHEMBL4258060 0.86 CYP3A4 (0.48) GLO1KMT2AMEN1NPSR1ALDH1A1
SCHEMBL4250580 0.86 CYP3A4 (0.48) GLO1KMT2AMEN1NPSR1ALDH1A1
SCHEMBL4250575 0.86 CYP3A4 (0.48) GLO1KMT2AMEN1NPSR1ALDH1A1
SCHEMBL4252686 0.85 BCL9 (0.52) KMT2AMEN1HPGDNPC1PKM
SCHEMBL4250585 0.85 BCL9 (0.52) KMT2AMEN1HPGDNPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL GLO1 3348/4885KMT2A 1072/4885MEN1 1358/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL GLO1 3348/4885KMT2A 1072/4885MEN1 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.