⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425613 | 1.00 | — | — | |
| SCHEMBL424063 | 0.82 | CHRNB2 (0.31) | — | |
| SCHEMBL424064 | 0.82 | CHRNB2 (0.31) | — | |
| SCHEMBL419251 | 0.79 | — | — | |
| SCHEMBL419252 | 0.79 | — | — | |
| SCHEMBL421339 | 0.78 | — | — | |
| SCHEMBL421338 | 0.78 | — | — | |
| SCHEMBL426321 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL426320 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL28055503 | 0.77 | CHRNB2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8291171-A | — | — | None | — | — | JP | disclosed |
| US-20120022053-A1 | Oxadiazine Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-26 | — | — | US | disclosed |
| US-7655650-B2 | Oxadiazine derivatives | Syngenta Corporation (US) | 2010-02-02 | — | — | US | disclosed |
| US-20070219188-A1 | Oxadiazine Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-09-20 | — | — | US | disclosed |
| US-20030232821-A1 | Oxadiazine derivatives | MAIENFISCH PETER (CH) | 2003-12-18 | — | — | US | disclosed |
| EP-0580553-B1 | Oxadiazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2003-11-26 | — | — | EP | disclosed |
| US-6627753-B1 | Agricultural insecticides | SYNGENTA INVESTMENT CORPORATION | 2003-09-30 | — | — | US | disclosed |
| US-6376487-B1 | SELECTIVE INSECTICIDES FOR KILLING FLIES, ROACHES, WEEVILS, AND OTHER PESTS; FOR USE ON COTTON, LEGUMES, FRUITS, CEREALS, BEANS, AND OTHER CROPS | SYNGENTA INVESTMENT CORP. | 2002-04-23 | — | — | US | disclosed |
| US-6022871-A | INSECTICIDES | NOVARTIS CORPORATION (US) | 2000-02-08 | — | — | US | disclosed |
| US-5852012-A | Oxadiazine derivatives | NOVARTIS CORPORATION (US) | 1998-12-22 | — | — | US | disclosed |
| JP-H08291171-A | INSECTICIDAL 5-((TETRAHYDRO-3-FURANYL)METHYL)-4-NITROIMINOPERPHYDRO-1,3,5-OXADIAZINE DERIVATIVE | MITSUI TOATSU CHEM INC | 1996-11-05 | — | — | JP | disclosed |
| EP-0580553-A2 | Oxadiazine derivatives | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |