SCHEMBL4256380

SCHEMBL4256380

CC(=O)OC(C)C/N=N/CC(C)OC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
CHRM2 P08172 2/20 0.52
CHRM4 P08173 2/20 0.52
CHRM1 P11229 2/20 0.52
TBXA2R P21731 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
GALR3 O60755 1/20 0.50
MAPT P10636 1/20 0.50
BLM P54132 1/20 0.50
ALOX15 P16050 1/20 0.38
TDP1 Q9NUW8 2/20 0.34
TRPV1 Q8NER1 1/20 0.34
LMNA P02545 3/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
HRH1 P35367 1/20 0.31
KMT2A Q03164 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4256383 1.00 TSHR (0.52) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10331178 0.81 TSHR (0.58) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL14087827 0.79 TSHR (0.56) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL766233 0.79 TSHR (0.56) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL16124233 0.78 TSHR (0.45) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL2355051 0.77 TSHR (0.54) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10804192 0.76 TSHR (0.58) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10793944 0.76 TSHR (0.58) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10796086 0.76 TSHR (0.58) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL3751182 0.75 TSHR (0.52) TSHRCHRM2CHRM4CHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2067175-A2 ELECTRONIC DEVICE MODULE COMPRISING POLYOLEFIN COPOLYMER Dow Global Technologies Inc. (US) 2009-06-10 EP disclosed
WO-2008036708-A2 ELECTRONIC DEVICE MODULE COMPRISING POLYOLEFIN COPOLYMER DOW GLOBAL TECHNOLOGIES INC. (US) 2008-03-27 WO disclosed
EP-1311609-A1 PEROXIDICALLY CROSS-LINKABLE COMPOSITIONS REHAU AG + Co (DE) 2003-05-21 EP disclosed
WO-2002018488-A1 PEROXIDICALLY CROSS-LINKABLE COMPOSITIONS REHAU AG + CO (DE) 2002-03-07 WO disclosed