SCHEMBL4256478

SCHEMBL4256478

CC/C=C/CCCC[Si](OC)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.43
LPAR3 Q9UBY5 3/20 0.43
LPAR1 Q92633 1/20 0.39
LMNA P02545 2/20 0.37
ALDH1A1 P00352 5/20 0.36
F7 P08709 3/20 0.36
F3 P13726 3/20 0.36
CYP19A1 P11511 3/20 0.36
MAPT P10636 2/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
OXER1 Q8TDS5 2/20 0.36
PTGS1 P23219 2/20 0.36
PPARG P37231 2/20 0.36
KMT2A Q03164 2/20 0.36
PPARD Q03181 2/20 0.36
PPARA Q07869 2/20 0.36
NR1I2 O75469 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4256481 1.00 LPAR2 (0.43) LPAR2LPAR3LPAR1LMNAALDH1A1
SCHEMBL31351383 0.93 LPAR2 (0.40) LPAR2LPAR3LPAR1LMNAALDH1A1
SCHEMBL29029659 0.85 LMNA (0.48) LPAR2LPAR3LPAR1LMNAF7
SCHEMBL2713411 0.85 LMNA (0.53) LPAR2LPAR3LPAR1LMNAF7
SCHEMBL28422758 0.84 LPAR2 (0.34) LPAR2LPAR3LPAR1LMNAALDH1A1
SCHEMBL467056 0.81 LPAR3 (0.42) LPAR2LPAR3LPAR1LMNAALDH1A1
SCHEMBL31351413 0.81 LPAR2 (0.38) LPAR2LPAR3LPAR1LMNAALDH1A1
SCHEMBL31351362 0.81 LPAR2 (0.38) LPAR2LPAR3LPAR1LMNAALDH1A1
SCHEMBL1196276 0.81 LMNA (0.32) LMNA
SCHEMBL467055 0.81 LPAR3 (0.42) LPAR2LPAR3LPAR1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815339-B2 Surface modifiers and process for surface modifications of particles of metal oxide using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-26 US claimed
EP-2062948-B1 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same KOREA INST SCI & TECH (KR) 2013-10-02 EP claimed
EP-2062948-A2 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same Korea Institute of Science and Technology (KR) 2009-05-27 EP claimed
US-20090130306-A1 SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) 2009-05-21 US claimed
US-8815339-B2 Surface modifiers and process for surface modifications of particles of metal oxide using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-08-26 US disclosed
EP-2062948-B1 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same KOREA INST SCI & TECH (KR) 2013-10-02 EP disclosed
EP-2062948-A2 Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same Korea Institute of Science and Technology (KR) 2009-05-27 EP disclosed
US-20090130306-A1 SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) 2009-05-21 US disclosed