Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 14/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258543 | 0.90 | CHRNA7 (0.42) | CHRNA7ACHECHRM3CHRM2 | |
| SCHEMBL321885 | 0.86 | CHRNA7 (0.48) | CHRNA7ACHECHRM3CHRM2 | |
| Iodide SCHEMBL195619 | 0.85 | CHRNA7 (0.47) | CHRNA7ACHECHRM3CHRM2 | |
| Bromide SCHEMBL1140066 | 0.85 | CHRNA7 (0.50) | CHRNA7ACHECHRM3CHRM2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8349313 | 0.84 | CHRNA7 (0.39) | CHRNA7ACHECHRM3CHRM2 | |
| SCHEMBL8346963 | 0.82 | CHRNA7 (0.43) | CHRNA7ACHECHRM3CHRM2 | |
| SCHEMBL4083156 | 0.77 | — | — | |
| SCHEMBL10256548 | 0.77 | CHRNA7 (0.52) | CHRNA7ACHECHRM3CHRM2 | |
| Hydrochloric Acid SCHEMBL11194479 | 0.76 | CHRNA7 (0.47) | CHRNA7ACHECHRM3 | |
| SCHEMBL10384394 | 0.74 | CHRNA7 (0.48) | CHRNA7ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081543-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | Henkel AG & Co. KGaA (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008095558-A2 | BLEACHING AGENT COMPRISING PIPERIDONE/S AND IMIDAZOLE/S | HENKEL AG & CO. KGAA (DE) | 2008-08-14 | — | — | WO | disclosed |