SCHEMBL4256758

SCHEMBL4256758

Cc1ccc(-n2c3ccc(-n4c5ccccc5c5cc(C)ccc54)cc3c3cc(-n4c5ccccc5c5cc(C)ccc54)ccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
MAPT P10636 5/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
BCHE P06276 2/20 0.40
ACHE P22303 2/20 0.40
PGR P06401 1/20 0.39
RORA P35398 1/20 0.39
RORC P51449 1/20 0.39
RORB Q92753 1/20 0.39
POLB P06746 1/20 0.39
METAP2 P50579 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
GAA P10253 1/20 0.38
KMT2A Q03164 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15606660 0.96 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL680510 0.96 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL16791299 0.96 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL27897 0.96 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL15747040 0.95 KDM4E (0.60) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL15785775 0.95 KDM4E (0.60) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL13957097 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL4251517 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL4402485 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL26226576 0.93 KDM4E (0.48) KDM4EL3MBTL1ATMMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090066224-A1 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES NAT1, SAT1, RIF1 KDM4E 1909/4885L3MBTL1 2488/4885ATM 1312/4885
US-20240025927-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 KDM4E 2492/4885L3MBTL1 462/4885ATM 3553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.