SCHEMBL27897

SCHEMBL27897

Cc1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
ATM Q13315 1/20 0.55
MAPT P10636 6/20 0.46
HTT P42858 3/20 0.46
LMNA P02545 2/20 0.46
POLB P06746 2/20 0.41
METAP2 P50579 1/20 0.40
GAA P10253 1/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GPR3 P46089 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16791299 1.00 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL15606660 1.00 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL4256758 0.96 KDM4E (0.52) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL26624919 0.93 KDM4E (0.48) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL680510 0.93 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL23616237 0.92 KDM4E (0.47) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL15785775 0.91 KDM4E (0.60) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL15747040 0.91 KDM4E (0.60) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL4251517 0.91 KDM4E (0.57) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL19863530 0.91 KDM4E (0.57) KDM4EL3MBTL1ATMMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3288094-B1 LIGHT EMITTING ELEMENT AND COMPOSITION USED IN SAID LIGHT EMITTING ELEMENT SUMITOMO CHEMICAL CO (JP) 2020-06-10 EP disclosed
US-10644243-B2 N-phenyl triscarbazole NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-05-05 US disclosed
US-20190259964-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2019-08-22 US disclosed
EP-2797871-B1 CROSSLINKABLE ARYLAMINE COMPOUNDS NISSAN CHEMICAL IND LTD (JP) 2018-05-09 EP disclosed
US-20180123056-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-03 US disclosed
EP-3288094-A1 LIGHT EMITTING ELEMENT AND COMPOSITION USED IN SAID LIGHT EMITTING ELEMENT Sumitomo Chemical Company Limited (JP) 2018-02-28 EP disclosed
WO-2017216168-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2017-12-21 WO disclosed
EP-3257849-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM Solvay SA (BE) 2017-12-20 EP disclosed
EP-2609080-B1 N-PHENYL TRISCARBAZOLE SOLVAY (BE) 2016-03-30 EP disclosed
EP-2609080-B1 N-PHENYL TRISCARBAZOLE SOLVAY (BE) 2016-03-30 EP disclosed
US-20150094437-A1 CROSSLINKABLE ARYLAMINE COMPOUNDS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-02 US disclosed
US-20150094437-A1 CROSSLINKABLE ARYLAMINE COMPOUNDS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-04-02 US disclosed
EP-2688117-A1 Process for forming a layer of an organic electronic device SOLVAY SA (BE) 2014-01-22 EP disclosed
WO-2013098175-A1 CROSSLINKABLE ARYLAMINE COMPOUNDS SOLVAY SA (BE) 2013-07-04 WO disclosed
EP-2609080-A1 N-PHENYL TRISCARBAZOLE Solvay SA (BE) 2013-07-03 EP disclosed
EP-2433928-A1 N-phenyl triscarbazole Solvay SA (BE) 2012-03-28 EP disclosed
WO-2012025510-A1 N-PHENYL TRISCARBAZOLE SOLVAY SA (BE) 2012-03-01 WO disclosed
WO-2012025510-A1 N-PHENYL TRISCARBAZOLE SOLVAY SA (BE) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10644243-B2 N-phenyl triscarbazole RB1, LBR, NR1I2 KDM4E 1474/4885L3MBTL1 977/4885ATM 2980/4885
US-20180123056-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE CHRM1, CRY1, L1CAM KDM4E 3757/4885L3MBTL1 280/4885ATM 1851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.