Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1706642 | 0.98 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| Hydrochloric Acid SCHEMBL25407374 | 0.95 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| SCHEMBL11546415 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| SCHEMBL7159906 | 0.80 | — | — | |
| SCHEMBL14549470 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRTP53HIF1A | |
| SCHEMBL12928715 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| SCHEMBL22360354 | 0.77 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| SCHEMBL31302979 | 0.77 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| SCHEMBL2862694 | 0.77 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2TSHRMAPK1USP2 | |
| 4-Chloroaniline SCHEMBL10577680 | 0.77 | PHGDH (0.45) | ALDH1A1SMN1; SMN2TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005355-A1 | Piperidine Compound and Process for Preparing the Same | TANABE SEIYAKU CO., LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-1765780-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006004195-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005355-A1 | Piperidine Compound and Process for Preparing the Same | AVPR1B, HRH4, PRLHR | ALDH1A1 2868/4885SMN1; SMN2 4150/4885TSHR 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.