Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.59 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938401 | 0.87 | ALDH1A1 (0.67) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL10939041 | 0.86 | ALDH1A1 (0.65) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL22171794 | 0.82 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL8685817 | 0.81 | ALDH1A1 (0.38) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL1444357 | 0.80 | ALDH1A1 (0.60) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL10942535 | 0.80 | ALDH1A1 (0.83) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL9512944 | 0.78 | ALDH1A1 (0.62) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL20904106 | 0.77 | ALDH1A1 (0.53) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL14571071 | 0.77 | ALDH1A1 (0.49) | ALDH1A1ALDH1A3ALDH3A1KDM4EGAA | |
| SCHEMBL8688587 | 0.77 | CYP1A2 (0.41) | ALDH1A1KDM4EGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648332-B2 | Phenyltetraene-based nonlinear optical chromophores | UNIVERSITY OF WASHINGTON (US) | 2014-02-11 | — | — | US | disclosed |
| US-8394499-B2 | Crosslinkable polymer host having pendant nonlinear optical chromophores and containing a nonlinear optical chromophore guest | UNIVERSITY OF WASHINGTON (US) | 2013-03-12 | — | — | US | disclosed |
| US-20090148717-A1 | CROSSLINKABLE POLYMER HOST HAVING PENDANT NONLINEAR OPTICAL CHROMOPHORES AND CONTAINING A NONLINEAR OPTICAL CHROMOPHORE GUEST | WASHINGTON, UNIVERSITY OF (US) | 2009-06-11 | — | — | US | disclosed |
| US-5834575-A | POLYIMIDE OR POLYACRYLATE WITH PENDANT GROUP CONTAINING THIOPHENE RING, BENZENE RING AND VICINAL NITRILE GROUPS, SWITCHES FOR OPTICAL SIGNALS, COMMUNICATION TECHNOLOGY | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-11-10 | — | — | US | disclosed |