Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.67 |
| ▸ | MAOB | P27338 | 4/20 | 0.67 |
| ▸ | MAOA | P21397 | 3/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257203 | 1.00 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL4266648 | 0.96 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL4266649 | 0.96 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL4604973 | 0.91 | KDM1A (0.61) | KDM1AMAOBMAOAHTR2C | |
| SCHEMBL6755876 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL5729043 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL7094099 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL18596475 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL26456133 | 0.80 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2CSLC6A2 | |
| SCHEMBL4253059 | 0.80 | HTR2C (0.55) | KDM1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833782-B1 | CYCLOALKYLAMINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-04-08 | — | — | EP | disclosed |