Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266648 | 0.95 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2CNOS3 | |
| SCHEMBL4266649 | 0.95 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2CNOS3 | |
| SCHEMBL4257207 | 0.91 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2C | |
| SCHEMBL4257203 | 0.91 | KDM1A (0.67) | KDM1AMAOBMAOAHTR2C | |
| SCHEMBL4608227 | 0.80 | KDM1A (0.40) | KDM1AMAOBMAOA | |
| SCHEMBL4606554 | 0.79 | KDM1A (0.66) | KDM1AMAOBMAOAHTR2CNPC1 | |
| SCHEMBL4604971 | 0.77 | SLC6A2 (0.52) | KDM1AMAOBMAOAHTR2CNPC1 | |
| SCHEMBL7094099 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2C | |
| SCHEMBL6755876 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2C | |
| SCHEMBL5729043 | 0.76 | KDM1A (1.00) | KDM1AMAOBMAOAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | claimed |
| US-6639107-B1 | Potentiating glutamate receptor function | ELI LILLY AND COMPANY | 2003-10-28 | — | — | US | claimed |
| EP-1246797-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001042203-A1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | claimed |
| EP-1246797-B1 | CYCLOPENTYL SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2008-07-23 | — | — | EP | disclosed |