Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592569 | 0.96 | MAPT (0.33) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3601526 | 0.82 | NPC1 (0.30) | SMN1; SMN2 | |
| SCHEMBL5923637 | 0.80 | NPC1 (0.30) | KMT2A | |
| SCHEMBL3601529 | 0.78 | NPC1 (0.30) | SMN1; SMN2 | |
| SCHEMBL4265629 | 0.77 | — | — | |
| SCHEMBL7177847 | 0.76 | — | — | |
| SCHEMBL4964252 | 0.72 | — | — | |
| SCHEMBL6810396 | 0.70 | MEN1 (0.35) | KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL4665366 | 0.70 | — | — | |
| SCHEMBL6413204 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499622-B1 | HETEROTRICYCLYL 6-ALKYLIDENE-PENEMS AS BETA-LACTAMASE INHIBITORS | WYETH CORP (US) | 2009-03-11 | — | — | EP | disclosed |