Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586645 | 0.97 | NPC1 (0.31) | NPC1KMT2A | |
| SCHEMBL6810143 | 0.87 | — | — | |
| SCHEMBL5923380 | 0.85 | POLB (0.32) | NPC1 | |
| SCHEMBL3592569 | 0.84 | MAPT (0.33) | KMT2A | |
| SCHEMBL5923640 | 0.82 | — | — | |
| SCHEMBL3555646 | 0.79 | NPC1 (0.33) | NPC1KMT2A | |
| SCHEMBL3588884 | 0.78 | L3MBTL1 (0.32) | — | |
| SCHEMBL4794959 | 0.77 | POLB (0.37) | NPC1KMT2A | |
| SCHEMBL3555003 | 0.77 | POLB (0.37) | NPC1KMT2A | |
| SCHEMBL3555002 | 0.77 | POLB (0.37) | NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276446-A1 | Tricyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors | WYETH (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276446-A1 | Tricyclic 6-alkylidene-penems as class-D beta-lactamases inhibitors | PEPD, PGLS, MGAM | NPC1 2769/4885KMT2A 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.