Ethylene

Ethylene

SCHEMBL4257350

C=C.CC(=O)Oc1ccc(N)cc1.CC(=O)Oc1ccc(N)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
CYP19A1 P11511 1/20 0.56
MAPT P10636 4/20 0.53
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
ELANE P08246 2/20 0.52
HSD17B10 Q99714 1/20 0.50
GAA P10253 2/20 0.48
ALDH1A1 P00352 2/20 0.48
HSP90AA1 P07900 1/20 0.48
KDM4E B2RXH2 3/20 0.47
CYP3A4 P08684 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TTR P02766 1/20 0.47
TP53 P04637 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GLA P06280 2/20 0.46
CUL4A Q13619 1/20 0.45
TDP1 Q9NUW8 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222240 0.96 LMNA (0.64) LMNACYP19A1MAPTPOLBPKM
SCHEMBL28066736 0.93 LMNA (0.61) LMNACYP19A1MAPTPOLBPKM
SCHEMBL1044505 0.93 LMNA (0.61) LMNACYP19A1MAPTPOLBPKM
Hydrochloric Acid SCHEMBL28309210 0.93 LMNA (0.61) LMNACYP19A1MAPTPOLBPKM
SCHEMBL11456568 0.93 LMNA (0.61) LMNACYP19A1MAPTPOLBPKM
SCHEMBL28079084 0.93 LMNA (0.61) LMNACYP19A1MAPTPOLBPKM
SCHEMBL3790234 0.89 HSD17B10 (0.63) LMNACYP19A1MAPTPOLBPKM
Nitrous Acid SCHEMBL27759330 0.88 LMNA (0.55) LMNACYP19A1MAPTPOLBPKM
SCHEMBL11815102 0.86 MAPT (0.56) LMNACYP19A1MAPTPOLBPKM
Aminobenzoic Acid SCHEMBL7049544 0.84 HSD17B10 (0.73) LMNACYP19A1MAPTPOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507784-B2 Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2009-03-24 US disclosed
US-20050209429-A1 Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2005-09-22 US disclosed
US-6939940-B2 Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2005-09-06 US disclosed
EP-1320567-A1 LIQUID CRYSTALLINE THERMOSETS FROM ESTER, ESTER-IMIDE, AND ESTER-AMIDE OLIGOMERS The Government of the United States of America as represented by the Administrator of the National Aeronautics and Space Adm. (US) 2003-06-25 EP disclosed
US-20020132933-A1 Liquid crystalline thermosets from ester, ester-imide, and ester-amide oligomers UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2002-09-19 US disclosed
WO-2002022706-A1 LIQUID CRYSTALLINE THERMOSETS FROM ESTER, ESTER-IMIDE, AND ESTER-AMIDE OLIGOMERS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (NASA) (US) 2002-03-21 WO disclosed