SCHEMBL425741

SCHEMBL425741

[NH]C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
FABP5 Q01469 3/20 0.54
FABP7 O15540 2/20 0.54
EPHX2 P34913 1/20 0.51
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
HTR2A P28223 1/20 0.44
CASP3 P42574 2/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15981181 0.85 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL44676 0.85 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29381061 0.83 FABP5 (0.59) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL44677 0.83 FABP5 (0.59) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29901230 0.83 FABP5 (0.59) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL30667581 0.83 KMT2A (0.56) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL2782675 0.83 KMT2A (0.56) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL12016740 0.83 KMT2A (0.56) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL9328044 0.82 PPARG (0.42) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL17703893 0.81 KMT2A (0.55) KMT2AFABP5FABP7EPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024120466-A1 MONOSACCARIDES, PHARMACEUTICAL COMPOSITIONS, AND DIAGNOSTIC AND THERAPEUTIC APPLICATIONS SURIO THERAPEUTICS CO., LTD (CN) 2024-06-13 WO claimed
CN-115650827-B Preparation method, intermediate compound and synthesis method for anthracycline derivatives 戊言医药科技(上海)有限公司 2024-03-15 CN claimed
US-20230391997-A1 FLOW CELL INCLUDING A HETEROPOLYMER ILLUMINA CAMBRIDGE LIMITED (GB) 2023-12-07 US claimed
US-11787930-B2 Flow cell including a heteropolymer ILLUMINA INC. (US) 2023-10-17 US claimed
CN-115651043-A Preparation method of anthracycline derivative 戊言医药科技(上海)有限公司 2023-01-31 CN claimed
CN-115650827-A Preparation method, intermediate compound and synthesis method for anthracycline derivatives 戊言医药科技(上海)有限公司 2023-01-31 CN claimed
CN-114853822-A Oligonucleotide-disulfide and synthetic method thereof 康龙化成(宁波)科技发展有限公司 2022-08-05 CN claimed
EP-3911686-A1 FLOW CELL INCLUDING A HETEROPOLYMER Illumina, Inc. (US) 2021-11-24 EP claimed
CN-112673034-A Flow cell comprising heteropolymers 伊鲁米那股份有限公司 2021-04-16 CN claimed
CN-108070009-B Method for preparing DNA coding compound library and initial fragment compound and prepared DNA coding compound 上海药明康德新药开发有限公司 2021-04-13 CN claimed
EP-0354522-A1 Use of alpha-aminoboronic acid derivatives in prevention and treatement of viral diseases HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-14 EP claimed
US-4855286-A HYPOTENSIVE AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0315574-A2 Renin inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-10 EP claimed
EP-0310015-A2 Renin-inhibiting dipeptides, process for their preparation, medicines containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-05 EP claimed
EP-0255082-A2 Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1988-02-03 EP claimed
EP-0239874-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their application HOECHST AKTIENGESELLSCHAFT (DE) 1987-10-07 EP claimed
EP-0230242-A2 Substituted derivatives of 4-amino-3-hydroxy-butyric acid, process for their production, medicines containing them, and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-29 EP claimed
EP-0073828-A4 HIGH PERFORMANCE PEPTIDE SYNTHESIS. BIORES INC (US) 1983-11-09 EP claimed
EP-0073828-A1 HIGH PERFORMANCE PEPTIDE SYNTHESIS BIORESEARCH INC. (US) 1983-03-16 EP claimed
WO-1982003077-A1 HIGH PERFORMANCE PEPTIDE SYNTHESIS BIORESEARCH INC (US) 1982-09-16 WO claimed