Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.81 |
| ▸ | RAB9A | P51151 | 5/20 | 0.81 |
| ▸ | TP53 | P04637 | 4/20 | 0.81 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.77 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.77 |
| ▸ | NT5E | P21589 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30048093 | 1.00 | NPC1 (0.81) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL5380687 | 0.90 | TP53 (1.00) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL30555199 | 0.90 | TP53 (1.00) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL30608967 | 0.89 | KCNK3 (0.87) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL259666 | 0.89 | KCNK3 (0.87) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL16675166 | 0.89 | KCNK3 (0.89) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL12259119 | 0.88 | TP53 (0.78) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL7822889 | 0.88 | MEN1 (0.78) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL14531871 | 0.88 | TP53 (0.74) | NPC1RAB9ATP53KCNK3KCNK9 | |
| SCHEMBL677855 | 0.88 | TP53 (0.74) | NPC1RAB9ATP53KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304507-A | Synthesis method of N-substituted aryl formamide | 兰州石化职业技术大学 | 2022-11-08 | — | — | CN | disclosed |
| EP-3187490-A1 | SUBSTITUTED BENZAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2017-07-05 | — | — | EP | disclosed |
| EP-1773786-B1 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-26 | — | — | EP | disclosed |
| US-9321766-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20160096832-A1 | KINASE INHIBITORS | ALLERGAN, INC. | 2016-04-07 | — | — | US | disclosed |
| US-20160082699-A1 | RESIN LAYER-ATTACHED SUPPORTING SUBSTRATE AND METHOD FOR PRODUCING SAME, GLASS LAMINATE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ELECTRONIC DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-03-24 | — | — | US | disclosed |
| US-20160082699-A1 | RESIN LAYER-ATTACHED SUPPORTING SUBSTRATE AND METHOD FOR PRODUCING SAME, GLASS LAMINATE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ELECTRONIC DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-03-24 | — | — | US | disclosed |
| US-20160075110-A1 | FLEXIBLE SUBSTRATE AND METHOD FOR PRODUCING SAME, GLASS LAMINATE AND METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING ELECTRONIC DEVICE | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-03-17 | — | — | US | disclosed |
| US-8357210-B2 | Disazo acid dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2013-01-22 | — | — | US | disclosed |
| EP-2027213-B1 | DISAZO ACID DYES | CLARIANT FINANCE BVI LTD (VG) | 2012-11-21 | — | — | EP | disclosed |
| US-7754196-B2 | Cosmetic composition comprising fiber | L'OREAL (FR) | 2010-07-13 | — | — | US | disclosed |
| US-20090126128-A1 | Disazo Acid Dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-05-21 | — | — | US | disclosed |
| US-20090126128-A1 | Disazo Acid Dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2009-05-21 | — | — | US | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | US | disclosed |
| US-7157548-B2 | Crosslinked sulfonated polyimide films | HANYANG HAK WON CO., LTD. (KR) | 2007-01-02 | — | — | US | disclosed |
| US-7157548-B2 | Crosslinked sulfonated polyimide films | HANYANG HAK WON CO., LTD. (KR) | 2007-01-02 | — | — | US | disclosed |
| WO-2003007954-A2 | SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036420-A1 | BENZAMIDE DERIVATIVES AND THEIR USE FOR TREATING CNS DISORDERS | GABBR1, GABBR2, CHRM2 | NPC1 869/4885RAB9A 733/4885TP53 4869/4885 |
| US-20160096832-A1 | KINASE INHIBITORS | ABL1, LCK, ERBB2 | NPC1 4204/4885RAB9A 2799/4885TP53 147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.