Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257792 | 1.00 | HDAC4 (0.49) | HDAC4HDAC1EPHX1TGM2SMN1; SMN2 | |
| SCHEMBL1445009 | 0.99 | HDAC4 (0.51) | HDAC4HDAC1EPHX1TGM2SMN1; SMN2 | |
| SCHEMBL2812234 | 0.99 | HDAC4 (0.51) | HDAC4HDAC1EPHX1TGM2SMN1; SMN2 | |
| SCHEMBL5740541 | 0.92 | HDAC4 (0.54) | HDAC4HDAC1EPHX1TGM2SMN1; SMN2 | |
| SCHEMBL2808344 | 0.86 | HDAC4 (0.49) | HDAC4HDAC1EPHX1SMN1; SMN2CASP1 | |
| SCHEMBL2808340 | 0.86 | HDAC4 (0.49) | HDAC4HDAC1EPHX1SMN1; SMN2CASP1 | |
| SCHEMBL693600 | 0.85 | HDAC4 (0.45) | HDAC4HDAC1EPHX1TGM2SMN1; SMN2 | |
| SCHEMBL8158076 | 0.84 | HDAC4 (0.47) | HDAC4HDAC1EPHX1SMN1; SMN2CASP1 | |
| SCHEMBL12709002 | 0.83 | EPHX1 (0.40) | HDAC4HDAC1EPHX1SMN1; SMN2ITGB3 | |
| SCHEMBL28263995 | 0.82 | HDAC4 (0.52) | HDAC4HDAC1EPHX1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |