Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
| ▸ | HEXA | P06865 | 5/20 | 0.58 |
| ▸ | HEXB | P07686 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | OGA | O60502 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699242 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPT | |
| SCHEMBL3435525 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPT | |
| SCHEMBL17280822 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPT | |
| SCHEMBL4438479 | 0.77 | ALDH1A1 (0.61) | CYP1B1HEXAHEXBALDH1A1HPGD | |
| SCHEMBL28795701 | 0.77 | CYP1B1 (0.54) | CYP1B1HEXAHEXBALDH1A1HPGD | |
| SCHEMBL9401924 | 0.77 | HEXA (0.50) | CYP1B1HEXAHEXBALDH1A1HPGD | |
| SCHEMBL9401920 | 0.77 | HEXA (0.50) | CYP1B1HEXAHEXBALDH1A1HPGD | |
| SCHEMBL117049 | 0.77 | CYP1B1 (1.00) | CYP1B1HEXAHEXBALDH1A1HPGD | |
| SCHEMBL10795642 | 0.77 | CYP1B1 (0.67) | CYP1B1HEXAHEXBALDH1A1HPGD | |
| SCHEMBL11678307 | 0.77 | HEXA (0.73) | CYP1B1HEXAHEXBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |