SCHEMBL4258412

SCHEMBL4258412

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nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.48
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 1/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
AKR1B1 P15121 1/20 0.35
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15948731 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29502274 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29506762 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL818364 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL5919108 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL29375023 1.00 PDE4A (0.48) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL2937201 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9818719 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL28085169 0.93 PDE4A (0.58) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL11274065 0.91 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778580-B1 SYNTHESIS OF FURANS FROM SUGARS VIA KETO INTERMEDIATES BP CORP NORTH AMERICA INC (US) 2025-12-17 EP disclosed
US-20090163442-A1 TREATMENT OF CANCER WITH 2-DEOXYGALACTOSE LANDAU BERNARD R 2009-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163442-A1 TREATMENT OF CANCER WITH 2-DEOXYGALACTOSE ST6GAL1, B4GALT1, GALK1 PDE4A 2045/4885LMNA 4077/4885L3MBTL1 526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.