⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489503 | 1.00 | — | — | |
| SCHEMBL822429 | 1.00 | — | — | |
| SCHEMBL93407 | 1.00 | — | — | |
| SCHEMBL30033233 | 1.00 | — | — | |
| SCHEMBL842357 | 0.97 | — | — | |
| SCHEMBL8723287 | 0.97 | — | — | |
| SCHEMBL18259771 | 0.84 | ALDH1A1 (0.41) | — | |
| Tetrahydrofuran SCHEMBL8912584 | 0.81 | ALDH1A1 (0.40) | — | |
| SCHEMBL3668894 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL17953985 | 0.77 | PTPN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983507-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 2000-03-08 | — | — | EP | claimed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-9703223-B2 | Toner, developer, and toner cartridge | HODOGAYA CHEMICAL CO., LTD. (JP) | 2017-07-11 | — | — | US | disclosed |
| US-20160209769-A1 | TONER, DEVELOPER, AND TONER CARTRIDGE | HODOGAYA CHEMICAL CO., LTD (JP) | 2016-07-21 | — | — | US | disclosed |
| US-8741917-B2 | Benzo [C] phenanthridines as antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120022061-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUGTERS, THE STATE UNIVERSITY OF NEW JERSEY | 2012-01-26 | — | — | US | disclosed |
| EP-2387564-A1 | BENZO ÝC¨PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | Rutgers, The State University of New Jersey (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8037884-B2 | Modular system for patient positioning during medical procedures | ALLEN MEDICAL SYSTEMS, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083436-A1 | BENZO [C] PHENANTHRIDINES AS ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-07-22 | — | — | WO | disclosed |
| US-20100064576-A1 | OLIGO- OR POLYAMINES AS OXIDATION STABILIZERS FOR BIOFUEL OILS | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |
| EP-0983507-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0968302-A1 | METHOD FOR PRODUCING ESTERS FREE OF ENANTIOMERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-05 | — | — | EP | disclosed |
| EP-0966469-A1 | METHOD FOR PRODUCING HETEROAROMATIC ALCOHOLS FREE OF ENANTIOMERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-29 | — | — | EP | disclosed |
| US-5925527-A | SCREENING NEW PHARMACEUTICALS | TREGA BIOSCIENCES, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0925368-A1 | METHOD FOR PRODUCING ALCOHOLS FREE OF ENANTIOMERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998037081-A1 | METHOD FOR PRODUCING HETEROAROMATIC ALCOHOLS FREE OF ENANTIOMERS | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |
| WO-1998037221-A1 | METHOD FOR PRODUCING ALCOHOLS FREE OF ENANTIOMERS | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |
| WO-1998037225-A1 | METHOD FOR PRODUCING ESTERS FREE OF ENANTIOMERS | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-27 | — | — | WO | disclosed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |