Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 4/20 | 0.64 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936170 | 0.87 | CCR10 (0.49) | CCR10CCKBRCCR1ALDH1A1HPGD | |
| SCHEMBL15935981 | 0.85 | CCR10 (0.50) | CCR10CCKBRCCR1ALDH1A1HPGD | |
| SCHEMBL1336196 | 0.84 | CCR10 (0.81) | CCR10ALDH1A1 | |
| SCHEMBL15943414 | 0.83 | CCR10 (0.60) | CCR10ALDH1A1HPGDMEN1LMNA | |
| SCHEMBL15943397 | 0.83 | CCR10 (0.57) | CCR10CCKBRCCR1ALDH1A1HPGD | |
| SCHEMBL1337631 | 0.82 | CCR10 (0.75) | CCR10 | |
| SCHEMBL1336050 | 0.82 | CCR10 (0.71) | CCR10 | |
| SCHEMBL15943436 | 0.81 | CCR10 (0.60) | CCR10ALDH1A1HPGDMEN1LMNA | |
| SCHEMBL1338168 | 0.81 | CCR10 (0.70) | CCR10 | |
| SCHEMBL1335999 | 0.81 | CCR10 (0.82) | CCR10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294051-B1 | ALPHA-SUBSTITUTED N-SULFONYL GYLCINE AMIDES ANTAGONISTS OF CCR10, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR USING THEM | BOEHRINGER INGELHEIM INT (DE) | 2014-08-13 | — | — | EP | disclosed |
| WO-2009142984-A1 | ALPHA-SUBSTITUTED N-SULFONYL GYLCINE AMIDES ANTAGONISTS OF CCR10, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR USING THEM | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-26 | — | — | WO | disclosed |