Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR10 | P46092 | 3/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258599 | 0.87 | CCR10 (0.64) | CCR10CCKBRALDH1A1GAAHPGD | |
| SCHEMBL15935981 | 0.85 | CCR10 (0.50) | CCR10CCKBRALDH1A1GAAHPGD | |
| SCHEMBL15936141 | 0.80 | CCR10 (0.49) | CCR10CCKBRALDH1A1GAAHPGD | |
| SCHEMBL15936083 | 0.79 | ALDH1A1 (0.48) | CCR10ALDH1A1GAAHPGDP2RY12 | |
| SCHEMBL15936005 | 0.78 | CCR10 (0.48) | CCR10CCKBRALDH1A1GAAHPGD | |
| SCHEMBL1337248 | 0.77 | HPGD (0.40) | CCR10ALDH1A1GAAHPGDACHE | |
| SCHEMBL1336030 | 0.74 | CCR10 (0.66) | CCR10 | |
| SCHEMBL4254115 | 0.72 | HPGD (0.44) | CCR10ALDH1A1GAAHPGDACHE | |
| SCHEMBL1336196 | 0.72 | CCR10 (0.81) | CCR10ALDH1A1 | |
| SCHEMBL15943397 | 0.70 | CCR10 (0.57) | CCR10CCKBRALDH1A1HPGDCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294051-B1 | ALPHA-SUBSTITUTED N-SULFONYL GYLCINE AMIDES ANTAGONISTS OF CCR10, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR USING THEM | BOEHRINGER INGELHEIM INT (DE) | 2014-08-13 | — | — | EP | disclosed |