SCHEMBL4258763

SCHEMBL4258763

CC/C(O)=C(/C)C(=O)O.CCCC/C=C(\O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.43
FNTA P49354 2/20 0.39
FNTB P49356 2/20 0.39
GRIK1 P39086 1/20 0.39
THRB P10828 1/20 0.38
PGGT1B P53609 1/20 0.38
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
TSHR P16473 1/20 0.31
TERT O14746 2/20 0.31
GMNN O75496 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
APEX1 P27695 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648943 0.89 GRIK1 (0.36) EP300FNTAFNTBGRIK1THRB
SCHEMBL5077277 0.88 EP300 (0.42) EP300FNTAFNTBGRIK1THRB
SCHEMBL51444 0.84 EP300 (0.56) EP300GRIK1F7F3TSHR
SCHEMBL3015069 0.84 EP300 (0.56) EP300GRIK1F7F3TSHR
SCHEMBL18339300 0.81 EP300 (0.48) EP300FNTAFNTBGRIK1THRB
SCHEMBL5590448 0.81 GRIK1 (0.32) FNTAFNTBGRIK1THRBPGGT1B
SCHEMBL18339298 0.81 EP300 (0.48) EP300FNTAFNTBGRIK1THRB
SCHEMBL3985350 0.78 EP300 (0.65) EP300F7F3TERTGMNN
SCHEMBL3849978 0.78 EP300 (0.65) EP300F7F3TERTGMNN
Phosphoric Acid SCHEMBL10618622 0.77 EP300 (0.48) EP300GRIK1F7F3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3497146-A1 SILANE-FUNCTIONAL POLYMERIC POLYURETHANES Covestro Deutschland AG (DE) 2019-06-19 EP disclosed
WO-2018029197-A1 SILANE-FUNCTIONAL POLYMERIC POLYURETHANES COVESTRO DEUTSCHLAND AG (DE) 2018-02-15 WO disclosed
EP-2271686-B1 Aqueous polyurethane solutions BAYER MATERIALSCIENCE AG (DE) 2012-10-24 EP disclosed
EP-2268691-B1 AQUEOUS POLYURETHANE SOLUTIONS FOR POLYURETHANE SYSTEMS BAYER MATERIALSCIENCE AG (DE) 2012-09-26 EP disclosed
EP-2110396-A1 1K-PUR systems made from aqueous or water-soluble polyurethanes Bayer MaterialScience AG (DE) 2009-10-21 EP disclosed
EP-2110395-A1 Aqueous polyurethane solutions for polyurethane systems Bayer MaterialScience AG (DE) 2009-10-21 EP disclosed
EP-0236353-A1 PROCESS FOR THE PRODUCTION OF FOAMED PLASTICS Erwin Behn Verpackungsbedarf GmbH (DE) 1987-09-16 EP disclosed
WO-1987001710-A1 PROCESS FOR THE PRODUCTION OF FOAMED PLASTICS ERWIN BEHN VERPACKUNGSBEDARF GMBH (DE) 1987-03-26 WO disclosed