SCHEMBL1648943

SCHEMBL1648943

CC/C(O)=C(/C)C(=O)O.CCC/C=C(\O)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
EP300 Q09472 1/20 0.33
THRB P10828 1/20 0.32
PGGT1B P53609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4258763 0.89 EP300 (0.43) GRIK1FNTAFNTBEP300THRB
SCHEMBL6466744 0.87 FNTA (0.37) GRIK1GRIK2FNTAFNTBEP300
SCHEMBL5590448 0.84 GRIK1 (0.32) GRIK1GRIK2FNTAFNTBTHRB
SCHEMBL124588 0.83
SCHEMBL127948 0.83
SCHEMBL1043047 0.80 ALDH1A1 (0.42) GRIK1GRIK2EP300
SCHEMBL16090 0.78
SCHEMBL2568206 0.78
SCHEMBL214046 0.78
Methacrylic Acid SCHEMBL7700828 0.78 GRIK1 (0.39) GRIK1GRIK2FNTAFNTBEP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2482766-B1 CORRECTIVE TREATMENT OF FINGER- OR TOENAILS HILLEBRAND CHRISTA (DE) 2015-02-25 EP disclosed
EP-2482766-A1 METHOD FOR CORRECTING FINGERNAILS OR TOENAILS Hillebrand, Christa (DE) 2012-08-08 EP disclosed
WO-2011039243-A1 METHOD FOR CORRECTING FINGERNAILS OR TOENAILS HILLEBRAND CHRISTA (DE) 2011-04-07 WO disclosed
EP-1360245-B1 ADHESIVES FOR METAL-POLYMER COMPOSITES 3M ESPE AG (DE) 2004-07-14 EP disclosed