Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353900 | 0.79 | ADH1A (0.40) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL98092 | 0.79 | ADH1A (0.40) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL1524628 | 0.76 | CYP1A2 (0.48) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL1643889 | 0.73 | CYP1A2 (0.43) | CYP1A2SIGMAR1THRATHRBACHE | |
| SCHEMBL6266859 | 0.73 | CYP1A2 (0.33) | CYP1A2THRATHRB | |
| SCHEMBL13464765 | 0.70 | CYP1A2 (0.42) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL11741926 | 0.70 | CYP1A2 (0.42) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL1412706 | 0.70 | CYP1A2 (0.42) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL21964977 | 0.70 | CYP1A2 (0.42) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL7471784 | 0.70 | CYP1A2 (0.42) | CYP1A2SIGMAR1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312559-A1 | CATALYTIC ENANTIOSELECTIVE SILYLATIONS OF SUBSTRATES | NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312559-A1 | CATALYTIC ENANTIOSELECTIVE SILYLATIONS OF SUBSTRATES | LSS, COASY, CYP51A1 | CYP1A2 11/4885SIGMAR1 1642/4885ADH1B 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.