Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL991845 | 1.00 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL991668 | 1.00 | — | — | |
| Bicarbonate SCHEMBL675540 | 1.00 | — | — | |
| Bicarbonate SCHEMBL8533364 | 1.00 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL993315 | 1.00 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL4662237 | 1.00 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL993011 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28756020 | 1.00 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL991935 | 1.00 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL23728398 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105268422-B | The preparation method of isophorone catalyst | 中国石油化工股份有限公司 | 2018-09-14 | — | — | CN | claimed |
| CN-106498497-A | A kind of method for preparing granule single crystallization Co2Z hexad ferrite powder body | 扬州大学 | 2017-03-15 | — | — | CN | claimed |
| CN-116459650-A | Integrated system and process for capturing and utilizing flue gas carbon of cement kiln | 北京工业大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-106458964-B | The salt of halogen substituted heterocyclic compound | 宇部兴产株式会社 | 2019-11-22 | — | — | CN | disclosed |
| CN-109674795-A | Itraconazole composition and dosage form and its application method | 梅恩医药国际有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-105130788-B | The method for preparing 3,5- dimethyl dodecyl acid | 信越化学工业株式会社 | 2019-04-19 | — | — | CN | disclosed |
| CN-109305676-A | The minimizing technology of graphitic carbon in a kind of nano diamond ash material being simple and efficient | 南京金瑞立丰硬质材料科技有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108794114-A | A kind of germanic Nano sustained-release fertilizer and preparation method thereof | 薛合伦 | 2018-11-13 | — | — | CN | disclosed |
| CN-105268422-B | The preparation method of isophorone catalyst | 中国石油化工股份有限公司 | 2018-09-14 | — | — | CN | disclosed |
| CN-105206800-B | A method of lead-acid battery is prepared as the lead-acid battery of active material anode and using the anode using lead sulfate | 东南大学 | 2018-08-21 | — | — | CN | disclosed |
| CN-108026381-A | Azo-compound, ink composite, ink jet recording method and tingle body | 日本化药株式会社 | 2018-05-11 | — | — | CN | disclosed |
| CN-106498497-A | A kind of method for preparing granule single crystallization Co2Z hexad ferrite powder body | 扬州大学 | 2017-03-15 | — | — | CN | disclosed |
| CN-106458964-A | salts of halogen-substituted heterocyclic compounds | 宇部兴产株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-102482305-B | Synthesis of N4- (2, 2-dimethyl-4- [ (dihydrophosphonooxy) methyl ] -3-oxo-5-pyrido [1,4] oxazin-6-yl) -5-fluoro-N2- (3,4, 5-trimethoxyphenyl) -2, 4-pyrimidinediamine disodium salt | 里格尔药品股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| US-20090203697-A1 | HETEROCYCLIC TYPE CINNAMIDE DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-0945450-B1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO (JP) | 2005-05-11 | — | — | EP | disclosed |
| CN-1563146-A | Synthetic method of unsaturated hydrophilic methyl or ethyl terminated polyether | WANG WEISONG (CN) | 2005-01-12 | — | — | CN | disclosed |
| EP-0944614-B1 | BENZOTHIOPHENECARBOXAMIDE DERIVATIVES AND PGD2 ANTAGONISTS COMPRISING THEM | SHIONOGI & CO (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6069166-A | INHIBITORY ACTIVITY AGAINST INFILTRATION OF EOSIONOPHILS, AND ARE USEFUL AS DRUGS FOR TREATING NASAL BLOCKAGE | SHIONOGI & CO., LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0945450-A1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |