Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL991845 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL991668 | 1.00 | — | — | |
| Bicarbonate SCHEMBL675540 | 1.00 | — | — | |
| Bicarbonate SCHEMBL8533364 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL993315 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL993011 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28756020 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL991935 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL4258947 | 1.00 | — | — | |
| Bicarbonate SCHEMBL23728398 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018232275-A2 | ANTIMICROBIAL TREATMENT OF ANIMAL CARCASSES AND FOOD PRODUCTS | PEROXYCHEM LLC (US) | 2018-12-20 | — | — | WO | claimed |
| US-20180360060-A1 | ANTIMICROBIAL TREATMENT OF ANIMAL CARCASSES AND FOOD PRODUCTS | PEROXYCHEM LLC (US) | 2018-12-20 | — | — | US | claimed |
| EP-4097187-B1 | CMP COMPOSITION FOR POLISHING HARD MATERIALS | ENTEGRIS INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20240234817-A9 | LITHIUM AIR BATTERY WITH IMPROVED CYCLABILITY | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KP) | 2024-07-11 | — | — | US | disclosed |
| US-20240136589-A1 | LITHIUM AIR BATTERY WITH IMPROVED CYCLABILITY | KOREA ADVANCED INST SCI & TECH (KR) | 2024-04-25 | — | — | US | disclosed |
| US-11840645-B2 | CMP composition for polishing hard materials | ENTEGRIS, INC. (US) | 2023-12-12 | — | — | US | disclosed |
| US-11820918-B2 | Hard abrasive particle-free polishing of hard materials | ENTEGRIS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11793208-B2 | Antimicrobial treatment of animal carcasses and food products | EVONIK OPERATIONS GMBH (DE) | 2023-10-24 | — | — | US | disclosed |
| EP-4097187-A1 | CMP COMPOSITION FOR POLISHING HARD MATERIALS | Entegris, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| US-20210324238-A1 | HARD ABRASIVE PARTICLE-FREE POLISHING OF HARD MATERIALS | MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT | 2021-10-21 | — | — | US | disclosed |
| US-20210253454-A1 | MICELLAR DELIVERY METHOD | EVONIK OPERATIONS GMBH (DE) | 2021-08-19 | — | — | US | disclosed |
| WO-2014074612-A1 | SMOOTH DIAMOND SURFACES AND CMP METHOD FOR FORMING | SINMAT, INC. (US) | 2014-05-15 | — | — | WO | disclosed |
| US-20140124793-A1 | SMOOTH DIAMOND SURFACES AND CMP METHOD FOR FORMING | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-20120252213-A1 | CHEMICAL MECHANICAL POLISHING OF GROUP III-NITRIDE SURFACES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2012135342-A1 | CHEMICAL MECHANICAL POLISHING OF GROUP III-NITRIDE SURFACES | SINMAT, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| EP-1719429-B1 | COIN SEPARATION AND CLEANING CASE | SUGAWARA TOSHIAKI (JP) | 2008-12-31 | — | — | EP | disclosed |
| US-20070045081-A1 | Currency sorting/cleaning case and currency sorting case | SUGAWARA TOSHIAKI | 2007-03-01 | — | — | US | disclosed |
| EP-1719429-A1 | COIN SEPARATION AND CLEANING CASE, AND COIN SEPARATION CASE | Sugawara, Toshiaki (JP) | 2006-11-08 | — | — | EP | disclosed |
| US-6310026-B1 | USING AQUEOUS SOLUTION OF PEROXO ACID AND/OR A PEROXO ACID SALT, WASHING OF THE CLEANED INORGANIC FILLER WITH WATER, CLEANING OF IT WITH AN ORGANIC SOLVENT; DENTAL RESTORATIONS | GC CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| US-20010034309-A1 | Method of cleaning and surface processing of inorganic filler utility | GC CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253454-A1 | MICELLAR DELIVERY METHOD | PORCN, PRDX2, PRDX5 | CA1 1120/4885CA2 993/4885CA9 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.