Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819513 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL4258095 | 0.86 | KDM4E (0.50) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL10741209 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL1027809 | 0.85 | NPC1 (0.46) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL30007636 | 0.85 | NPC1 (0.46) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL5413239 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL10306224 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDKMT2AKDM4ENPC1 | |
| SCHEMBL28388030 | 0.82 | KMT2A (0.51) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL14565687 | 0.82 | PRKCI (0.43) | ALDH1A1HPGDKMT2AKDM4ENPC1 | |
| SCHEMBL1028607 | 0.81 | NPC1 (0.46) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069373-A1 | Quinoline Acids | NR1H3, NR1H2, NR1H4 | ALDH1A1 1667/4885HPGD 978/4885KMT2A 1078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.