Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261792 | 0.87 | ESR1 (0.42) | ESR1ESR2EPHX2PPARGTBXAS1 | |
| SCHEMBL4264978 | 0.86 | SNCA (0.37) | ESR1ESR2EPHX2PPARGTBXAS1 | |
| SCHEMBL4255146 | 0.86 | HSP90AA1 (0.37) | ESR1ESR2EPHX2PPARGTBXAS1 | |
| SCHEMBL5993797 | 0.79 | ALDH1A1 (0.53) | ESR1ESR2EPHX2PPARGTBXAS1 | |
| SCHEMBL3128764 | 0.79 | ALDH1A1 (0.53) | ESR1ESR2EPHX2PPARGTBXAS1 | |
| SCHEMBL10349544 | 0.79 | ALDH1A1 (0.53) | ESR1ESR2EPHX2PPARGTBXAS1 | |
| SCHEMBL4259402 | 0.78 | ESR1 (0.45) | ESR1ESR2TBXAS1PTGS2ALDH1A1 | |
| Gsk-232802 SCHEMBL3467757 | 0.78 | ESR1 (0.55) | ESR1PPARGKDM4EALDH1A1PGR | |
| SCHEMBL3467812 | 0.78 | ESR1 (0.55) | ESR1ESR2ALDH1A1CYP3A4PGR | |
| SCHEMBL3467807 | 0.78 | ESR1 (0.55) | ESR1ESR2ALDH1A1CYP3A4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569601-B2 | Cycloalkylidene compounds as modulators of estrogen receptor | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-04 | — | — | US | disclosed |
| US-20070213348-A1 | Chemical Compounds | BRITTON JONATHAN E | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213348-A1 | Chemical Compounds | GPER1, ESR2, ESR1 | ESR1 3/4885ESR2 2/4885EPHX2 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.