⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772602 | 0.91 | TSHR (0.39) | — | |
| SCHEMBL11894115 | 0.84 | — | — | |
| SCHEMBL1406575 | 0.84 | — | — | |
| SCHEMBL11894023 | 0.84 | — | — | |
| SCHEMBL1406777 | 0.79 | KCNA3 (0.44) | — | |
| SCHEMBL15415852 | 0.77 | HRH3 (0.36) | — | |
| SCHEMBL1448301 | 0.75 | KCNA3 (0.42) | — | |
| SCHEMBL510293 | 0.74 | — | — | |
| SCHEMBL1259723 | 0.74 | — | — | |
| SCHEMBL772552 | 0.74 | LTA4H (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | claimed |
| US-20230416258-A1 | BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-12-28 | — | — | US | claimed |
| EP-4242210-A1 | NEW BENZODIAZEPINE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | China Pharmaceutical University (CN) | 2023-09-13 | — | — | EP | claimed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | claimed |
| CN-116507628-A | Novel benzodiazepine compound, preparation method and application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | claimed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | claimed |
| EP-3749669-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2020-12-16 | — | — | EP | claimed |
| CN-111683950-A | AhR modulators | 伊迪亚生物科学有限公司 | 2020-09-18 | — | — | CN | claimed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | claimed |
| US-9573949-B2 | Derivatives of [1, 2, 4] triazolo [4, 3-a] pyridine as P38—MAP kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-02-21 | — | — | US | claimed |
| US-20090118305-A1 | PYRIDINE AND PYRAZINE DERIVATIVES - 083 | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | claimed |
| WO-2009053737-A2 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2009-04-30 | — | — | WO | claimed |
| US-20080108613-A1 | Pyrazolopyrimidine Compounds as Antitumor Agents | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | US | claimed |
| CN-101124228-A | Pyrazolopyrimidine compounds as antitumor agents | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | CN | claimed |
| EP-1838712-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2007-10-03 | — | — | EP | claimed |
| US-20070105859-A1 | 4-Phenylamino-benzaldoxime derivatives and uses thereof as mitogen-activated protein kinase kinase (mek) inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-05-10 | — | — | US | claimed |
| EP-1674452-A1 | NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND USE THEREOF AS MEK INHIBITOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-06-28 | — | — | EP | claimed |
| WO-2006064196-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | claimed |
| US-6768024-B1 | CONTROLLING OBESITY, SEXUAL DYSFUNCTION OR INFLAMMATION | LION BIOSCIENCE AG (DE) | 2004-07-27 | — | — | US | claimed |
| WO-2002012166-A2 | TRIAMINE DERIVATIVE MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | LION BIOSCIENCE AG (DE) | 2002-02-14 | — | — | WO | claimed |