Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 7/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254989 | 1.00 | CA1 (0.44) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL4259453 | 0.88 | TDP1 (0.44) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL4254984 | 0.88 | TDP1 (0.44) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL4256438 | 0.85 | CA1 (0.54) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL4258721 | 0.85 | CA1 (0.54) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL4254991 | 0.77 | IDO1 (0.40) | CA1CA2IDO1AGXTAPP | |
| SCHEMBL4253463 | 0.75 | TDP1 (0.49) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL26986201 | 0.74 | CA1 (0.50) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL8499580 | 0.74 | IDO1 (0.61) | CA1CA2TDP1L3MBTL1IDO1 | |
| SCHEMBL4256434 | 0.73 | CA1 (0.53) | CA1CA2TDP1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046098-A1 | NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |