Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.61 |
| ▸ | AGXT | P21549 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 7/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17230489 | 0.94 | TDP1 (0.56) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL17230490 | 0.92 | APP (0.56) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL17230498 | 0.92 | TDP1 (0.54) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL8368000 | 0.92 | APP (0.70) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL34413 | 0.90 | IDO1 (0.67) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL12462062 | 0.89 | TDP1 (0.56) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL16093231 | 0.88 | APP (0.57) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL16321948 | 0.88 | APP (0.57) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL15532301 | 0.88 | APP (0.57) | IDO1AGXTTDP1L3MBTL1APP | |
| SCHEMBL22704320 | 0.88 | APP (0.53) | IDO1AGXTTDP1L3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908768-A1 | Anticoagulant compounds | Endotis Pharma (FR) | 2008-04-09 | — | — | EP | disclosed |