Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399923 | 0.83 | KDM4E (0.58) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL4401354 | 0.78 | KDM4E (0.52) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL10660178 | 0.75 | MAPT (0.51) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL12289816 | 0.74 | KDM4E (1.00) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL24513417 | 0.73 | KDM4E (0.71) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL24513420 | 0.73 | KDM4E (0.71) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL24513181 | 0.73 | KDM4E (0.49) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23075994 | 0.72 | PDE1B (0.56) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL635537 | 0.72 | KDM4E (0.48) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9543555 | 0.72 | CYP1A2 (0.65) | CYP1A2CYP2C9KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |