SCHEMBL4259904

SCHEMBL4259904

C=C(CC)C(=O)OOc1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.40
TDP1 Q9NUW8 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 3/20 0.39
MAPK1 P28482 2/20 0.39
KDM4E B2RXH2 8/20 0.37
ALDH1A1 P00352 5/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
HTT P42858 2/20 0.35
KMT2A Q03164 2/20 0.35
PKM P14618 1/20 0.35
MEN1 O00255 1/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534828 0.87 L3MBTL1 (0.44) L3MBTL1TDP1SMN1; SMN2MAPTLMNA
SCHEMBL9985386 0.80 L3MBTL1 (0.46) L3MBTL1TDP1SMN1; SMN2LMNAMAPK1
Biphenyl SCHEMBL29274370 0.80 MAPT (0.42) L3MBTL1SMN1; SMN2MAPTALDH1A1PKM
SCHEMBL1043462 0.79 MAPT (0.45) L3MBTL1SMN1; SMN2MAPTLMNAALDH1A1
SCHEMBL134191 0.78 MAPT (0.40) L3MBTL1TDP1SMN1; SMN2MAPTALDH1A1
SCHEMBL29117762 0.76 L3MBTL1 (0.42) L3MBTL1TDP1SMN1; SMN2MAPTLMNA
SCHEMBL29048573 0.75 KDM4E (0.38) L3MBTL1TDP1SMN1; SMN2MAPTLMNA
SCHEMBL28452221 0.74 KDM4E (0.42) L3MBTL1TDP1SMN1; SMN2MAPTLMNA
SCHEMBL3929743 0.72 CA1 (0.41) L3MBTL1SMN1; SMN2MAPTLMNAMAPK1
SCHEMBL6394195 0.72 TDP1 (0.40) L3MBTL1TDP1SMN1; SMN2MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125914-A2 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS 3M Innovative Properties Company (US) 2009-12-02 EP disclosed
WO-2008112452-A2 TRIPHENYL MONOMERS SUITABLE FOR MICROSTRUCTURED OPTICAL FILMS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-09-18 WO disclosed